For further information and detailed documentation on the 4S-FE ECU pinout, consult:
factory service manuals, as these are the primary vehicles that featured the 4S-FE engine. 4E-FE ECU Pinout and Wiring Guide | PDF - Scribd
The 4S-FE often shares its layout with the 3S-FE (common in Camrys and Coronas). Common pin designations include: : +B / +B1 : Main power supply from the EFI main relay. BATT : Constant battery power for memory. E1 / E01 / E02 : Main ECU and power grounds. Signals :
Ground-side control for fuel injectors (often paired 1&3 and 2&4). Pressure Intake Manifold Signal from the MAP sensor for load calculation. THA Intake Air Temp Temperature signal from the air intake sensor. THW Water Temp