Most trainers for the "Uncaged Edition" offer a range of tactical advantages. Common options found in downloads from sites like StopGame and Gamepressure include:

Diet was considered even more critical than weightlifting for the lean, "shredded" look required for shirtless scenes. Hugh Jackman's Wolverine Meal Plan - Coach

By navigating to the game's Config folder, you can change mCombatHeroIsGod=False to True for God Mode or mCheatTalentsMax=False to True to max out your talents.

X, Sq, Circle, Sq, X, Triangle, X, Triangle, X, Sq, Circle, Circle, Sq, R3 Sources: GameFAQs , IGN , GameRevolution X-Men Origins: Wolverine – Guides and FAQs - GameFAQs