To comply with the Vitamin K3 USP monograph, a QC laboratory must follow the pharmacopeial procedures exactly. Modifications require full validation.
In the United States Pharmacopeia (USP), is officially cataloged under its chemical name, Menadione . The USP monograph establishes the legal and quality standards for the drug substance, ensuring its identity, strength, and purity. Core Identity & Chemical Profile Official Name : Menadione Chemical Name : 2-Methyl-1,4-naphthoquinone Molecular Formula : Molecular Weight : 172.18 CAS Number : 58-27-5 vitamin k3 usp monograph
% Assay (dried basis) = (% Assay (as is) × 100) / (100 - % Loss on Drying) To comply with the Vitamin K3 USP monograph,
A 10% (w/v) solution in acetone is clear and not more intensely colored than yellow. ensuring its identity