The Epr-18022.ic2 file is typically very small (often 8KB or 32KB). If a download link asks you to download an .exe or a massive file for this single ROM, it is likely malware.
When you download a MAME ROM set for a game like Moonwalker or Shinobi , you might find that the game fails to boot, showing a "Required Files Missing" error. Even if you have the main game zip file, MAME requires the file to handle the security handshake of the original hardware. Common Games Requiring This File: Michael Jackson's Moonwalker (Arcade version) Altered Beast (Certain regional revisions) Golden Axe (Specific bootlegs or versions) How to Install Epr-18022.ic2 in MAME Epr-18022.ic2 Mame Download
If you provide the you are using, I can give you the precise parent ROM name and the expected SHA1 for epr-18022.ic2 (without links). Let me know in a follow-up. The Epr-18022