: Serbuk hablur sangat halus, licin, mudah melekat pada kulit, bebas dari butiran, berwarna putih atau putih kelabu.
Asbes merupakan kontaminan berbahaya yang sering ditemukan dalam tambang talkum. Standar terbaru (terutama revisi USP yang akan berlaku penuh pada ) mewajibkan pengujian ketat: Talc - USP-NF
The stipulates that talc is obtained from natural sources by crushing, grinding, and micronizing. No surface treatment is permitted unless explicitly stated in the monograph for a specific functional grade. monografi talkum
Talkum merupakan mineral filosilikat (berserat lembaran). Struktur kristalnya terdiri dari satu lembaran kation magnesium diapit oleh dua lembaran silikat tetrahedral. Susunan ini menghasilkan sifat fisika yang sangat khas: permukaan yang licin, tidak reaktif secara kimia, dan hydrophob (tidak suka air). Struktur berlapis ini memungkinkan lembaran-lembaran talkum meluncur satu sama lain dengan mudah, yang menjadi dasar sifat pelumasnya.
(English: Talc) is a naturally occurring, hydrated magnesium silicate mineral with the chemical formula Mg₃Si₄O₁₀(OH)₂ . It is the softest known mineral (hardness 1 on the Mohs scale) and serves as the reference point for softness. In pharmaceutical, cosmetic, and industrial contexts, a monografi (monograph) provides a legally recognized set of specifications and standards to ensure identity, purity, and quality. The primary pharmacopoeias—European Pharmacopoeia (Ph. Eur.), United States Pharmacopeia (USP), and Indonesian Pharmacopoeia (Farmakope Indonesia)—contain dedicated monographs for Talcum . : Serbuk hablur sangat halus, licin, mudah melekat
Praktis tidak larut dalam air, dalam etanol (96%), serta dalam larutan asam dan alkali encer. Identifikasi Utama: Spektrum serapan inframerah menunjukkan pita maksimum pada Syarat Mutu Penting: bebas dari asbes Absence of Asbestos ) untuk menjamin keamanan penggunaan pada manusia. 💡 Kegunaan dalam Dunia Farmasi & Kosmetik Talkum bukan hanya pengisi, tapi memiliki fungsi krusial: Uraian dan Khasiat Talkum dalam Farmasi | PDF - Scribd
From regulatory inspection reports (FDA 483s and EudraGMDP), No surface treatment is permitted unless explicitly stated
| Property | Value/Description | |----------|------------------| | Appearance | White to greyish-white, fine, crystalline powder | | Odor/Taste | Odorless, tasteless | | Particle size | Typically >90% passes through 45 µm sieve (Ph. Eur.) | | Density | 2.58–2.83 g/cm³ | | Bulk density | ~0.2–0.4 g/cm³ (light) | | pH (10% aqueous suspension) | 7.0–9.5 | | Solubility | Insoluble in water, diluted acids, and alkalis; slightly soluble in concentrated strong acids | | Surface property | Hydrophobic, lipophilic, smooth, greasy feel | | Melting point | ~1500°C (decomposes) |
| Test | Limit | |------|-------| | Loss on ignition (600°C) | 4.0–6.5% (dehydroxylation) | | Acid-soluble matter (HCl) | ≤ 2.0% | | Water-soluble matter | ≤ 0.2% | | Iron (as Fe₂O₃) | ≤ 0.5% (varies by grade) | | Arsenic (As) | ≤ 3 ppm | | Lead (Pb) | ≤ 5–10 ppm | | Heavy metals (as Pb) | ≤ 20 ppm | | Microbiological quality | ≤ 10² CFU/g for TAMC, ≤ 10¹ CFU/g for TYMC; absence of E. coli , S. aureus , P. aeruginosa | | Asbestos (tremolite, actinolite, anthophyllite) | (most critical safety test) |