If the game won't launch on a 4K monitor, try temporarily setting your primary Windows display to 1080p before launching.
The most reliable community fix bypasses GFWL entirely. This does not remove save files or DLC but tricks the game into thinking GFWL is running. re5 steam fix
If you are still crashing after all this, post your re5_fix.log file to the Steam Community Hub—but statistically, these five methods fix 99% of all RE5 launch issues. If the game won't launch on a 4K